Environmental and (eco)toxicological Omics and Epigenetics: Science, Technology and Regulatory Applications

View the presentations from the symposium (for reasons of confidentiality, not all presentations are publicly available):  

Opening address

01 | Ecological and Evolutionary Genomics: from metabarcoding to causative nucleotide - Mark Blaxter (University of Edinburgh, UK)


Session 1: Microbial genomics and metagenomics

02 | The ocean microbial-environmental interactome - Gipsi Lima-Mendez (University of Leuven / Flemish Institute for Biotechnology (VIB), Belgium)

03 | Investigating the impacts of stress on the microbiome, immune status and disease resistance of Atlantic salmon - Tamsyn Uren Webster (Swansea University, UK)

04 | Dynamic changes in the strawberry rhizobiome in response to biochar - Caroline De Tender (ILVO, Belgium)

05 | The anaerobic digestion microbiome: between active and abundant microorganisms - Jo De Vrieze (Center for Microbial Ecology and Technology (CMET), Ghent University, Belgium)

06 | Automatic identification of causal mechanisms underlying experimentally evolved populations - Bram Weytjens (Deptartment of Plant Biotechnology and Bioinformatics, Ghent University, Belgium)

07 | Ingestion of microplastics by the freshwater invertebrate Chironomus sancticaroli: effects on PBDE bioaccumulation and the gut microbiome - Dave Spurgeon (Centre for Ecology and Hydrology, UK)

08 | Genotype-dependent gut microbiota drives zooplankton resistance to toxic cyanobacteria - Ellen Decaestecker (Laboratory of Aquatic Biology, Department of biology, University of Leuven - Campus Kulak, Belgium)


Session 2: Evolutionary and ecological omics

09 | Signatures of adaptive evolution in Collembola Genomes - Dick Roelofs (VU Amsterdam, The Netherlands)

10 | Inferring demographic histories from whole genome data - Konrad Lohse (Institute for Evolutionary Biology, Edinburgh University, UK)

11 | Genetic and plastic responses in Daphnia magna: comparison of clonal differences and environmental stress induced changes in alternative splicing and gene expression - Jouni Kvist (Institute of Biotechnology, University of Helsinki, Finland)

12 | Hook a worm to catch a man - David W. Stanton (Cardiff University, Organisms and Environment Department, UK)

13 | Field-realistic levels of neonicotinoids: assessing gene-networks in honeybees - Reinhard Stöger (University of Nottingham, UK)


Session 3: (Eco)toxicological omics

14 | Network analysis predicts genes associated with silver toxicity in Chlamydomonas reinhardtii - Anze Zupanic (Eawag, Switzerland)

15 | Ionising radiation induced stress responses in the macrophyte Lemna minor: comparison at different levels of biological complexity, from growth to gene expression - Nele Horemans (Biosphere Impact Studies, SCK•CEN, Belgium)

16 | Using transcriptomics to understand crustacean intersexuality: untangling feminisation, demasculinisation, parasitic and environmental influences - Stephen Short (Cardiff University, School of Biosciences, UK)

17 | Global transcriptional responses to repeated copper exposures in the three-spined stickleback (Gasterosteus aculeatus) - Eduarda M. Santos (University of Exeter, Biosciences Department, UK)

18 | The Value of (Eco)Toxicogenomics Realized: From Zero to Validated Adverse Outcome Pathway (AOP) with Genomics Guiding the Way - Kurt A. Gust (US Army, Engineer Research and Development Center, USA)

19 | Towards developing a Framework for transcriptomics and other Big Data analysis for regulatory application - Tim Gant (Publich Health England, UK)

20 | SETAC Global Advisory Group OMICS: Cutting-edge science to solve real world problems - Ben Brown (Lawrence Berkeley National Laboratory, USA)

21 | Delayed impacts of developmental exposure to 17-α-ethinylestradiol on the phenotype and the proteome of the self-fertilizing fish Kryptolebias marmoratus - Anne-Sophie Voisin (University of Namur, Belgium)

22 | Shotgun proteogenomics & multiplexed targeted proteomics define robust, specific protein biomarkers from non-model species for environmental monitoring - Duarte Gouveia (Irstea, Unité de Recherche MALY, Laboratoire d’écotoxicologie, France)

23 | Is protein carbonylation a sensitive effect marker of gamma irradiation damage? Comparison between acute and chronic irradiation - Cecile D. Dubois (Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Laboratoire d’ECOtoxicologie des radionucléides (LECO), France)

24 | Using an integrative OMICs approach to unravel Glyphosate mechanisms of toxicity in Folsomia candida - Tiago Simões (MARE–Marine and Environmental Sciences Centre, ESTM, Polytechnic Institute of Leira, Portugal)

25 | Multi-species metabolomics to enable the design of cost-effective biomonitoring programs for determining the impacts of pollution in estuarine environments - Sara Long (Centre for Aquatic Pollution Identification and Management, University of Melbourne, Australia)

26 | Peptidomics of the zebrafish: discovering neuropeptides by LC-MS - Steven J. Husson (Systemic Physiological & Ecotoxicological Research, University of Antwerp, Belgium)

27 | An integrated 'omics approach to elucidate low-dose effects of xenobiotics in zebrafish larvae (Danio rerio) - Susie S.Y. Huang (AXYS Analytical Services Ltd., Canada)

28 | Addressing a key challenge in non-targeted environmental metabolomics: identifying the parts list through Deep Metabolome Annotation - Mark Viant (University of Birmingham, UK)

29 | Epigenetic basis of honeybee development, behavior and health - Brian Herb (Johns Hopkins School of Medicine, USA)


Session 4: Epigenetics in ecology and (eco)toxicology: science and technology

30 | Epigenetics in (Eco-)Toxicology - Juliette Legler (Brunel University London, UK)

31 | Environment shapes genomes and epigenetic state: What does this mean for natural populations? - Joe Shaw (University of Indiana, USA)

32 | Epigenetics technologies in ecology and (eco)toxicology - Ben Brown (Lawrence Berkeley National Laboratory, USA)

33 | Technologies to study epigenetic traits in humans and environmental species - Emilia Danilowicz-Luebert (Diagenode s.a., Belgium)

34 | Towards a Generalised Method for Environmental Epigenetics: Global and Differential Genome-Wide Epigenetic Signatures in an Earthworm Exposed to a Multi-stressor Environment - Oliver Rimington (Cardiff University, UK)

35 | Environmental heat stress induces epigenetic inheritance of robustness in Artemia model - Parisa Norouzitallab (Laboratory of Aquaculture & Artemia Reference Center, Ghent University, Belgium)

36 | Is inbreeding and inbreeding depression associated with epigenetic regulation? A case study in Daphnia magna - Mieke Jansen (KULeuven, Belgium)


Session 5: Transgenerational and epigenetic effects of chemicals

37 | Mechanisms underlying epigenetic effects of endocrine disruptive chemicals - Joëlle Rüegg (Swedish Toxicology Science Research Center Swetox, Sweden)

38 | Exposure to copper during embryogenesis caused increased tolerance in subsequent generations, in the three-spined stickleback - Lauren Laing (University of Exeter, UK)

39 | DNA methylation in the model organism Daphnia magna - Camila Gonçalves Athanásio (School of Biosciences, University of Birmingham, UK)

40 | Differences between generations in the response to gamma irradiation in Arabidopsis thaliana - Jorden van de Walle (Belgian Nuclear Research Centre SCK•CEN, Belgium)

41 | The role of DNA methylation in AHR-mediated toxicity of PAHs in chicken embryo - Jessica A. Head (McGill University, Canada)

42 | Intergenerational metabolic reprogramming in flies - Adelheid Lempradl (Max Planck Institute of Immunobiology and Epigenetics, Germany)

43 | Effects of low dose gamma irradiation on histone modifications during zebrafish embryogenesis - Leif Christopher Lindeman (Norwegian University of Life Sciences, Norway)

44 | Differential DNA Methylation in F2 Generation Testicular Cells Caused by Embryonic Exposure to Bisphenol A at F0 Generation - Ramji  K. Bhandari (Department of Biology, University of North Carolina at Greensboro, USA)


Session 6: Epigenetics in risk assessment: academia, industry and regulator perspective

45a | Academia perspective - Peter Kille (Cardiff University, UK)

45b | Industry perspective - Alan Poole (ECETOC, Belgium)

45c | Government perspective - Gilbert Schönfelder (Federal Institute for Risk Assessment (BfR), Germany)

46 | Environmentally induced epigenetic toxicity: potential public health concerns - Emma Marczylo (Public Health England, UK)

47 | International regulatory needs for development of an IATA for non-genotoxic carcinogenic chemical substances - Miriam Jacobs (Centre for Radiation, Chemical and Environmental Hazards, Public Health England, UK)

48 | Report on EFSA scientific colloquium on epigenetics and risk assessment - Christer Hogstrand (King's College London, UK)